Advagraf 0.5mg Capsule

TACROLIMUS
₹412.30 ₹656.25 (You Save ₹244)

Sourced from: ASTELLAS PHARMA INC
37% OFF
★★★★★ 4.8 On Google
₹412.30 MRP: ₹656.25 37% OFF

Inclusive of all taxes

₹412.30/Unit
Rx Prescription Required
Salt Composition
TACROLIMUS
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Dispatch: Tomorrow
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Quick overview

Advagraf 0.5mg Capsule contains TACROLIMUS and is marketed by ASTELLAS PHARMA INC. Country of origin: India. This pack is , priced at ₹412.30 inclusive of all taxes (about 37% off MRP). A valid prescription is required to order this medicine. On MedsRight, Advagraf 0.5mg Capsule is organised under the Nephrology speciality and the Transplant condition category.

Know about Advagraf 0.5mg Capsule in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: TACROLIMUS — that is what goes into Advagraf 0.5mg Capsule as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹412.30 for , including all taxes. The MRP printed on the pack is ₹656.25 — you save roughly 37% versus that.

  • Per-unit value: Roughly ₹412.30 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Advagraf 0.5mg Capsule under “Nephrology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Transplant” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: ASTELLAS PHARMA INC is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Advagraf 0.5mg Capsule. Take it only the way your doctor told you.

  • Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Advagraf 0.5mg Capsule to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Advagraf 0.5mg Capsule contains tacrolimus, a powerful immunosuppressant medication that helps prevent your body from rejecting a transplanted organ. After organ transplantation (liver, kidney, heart, or other organs), your immune system may treat the new organ as foreign and try to attack it. Advagraf works by calming your immune response, allowing your body to accept and maintain the transplanted organ safely.

This medication belongs to a class of drugs called calcineurin inhibitors and is always used alongside other medicines as part of a complete transplant rejection prevention plan. It is essential to take Advagraf exactly as prescribed by your doctor and continue taking it long-term to protect your transplanted organ.

Key points

  • Prevents organ transplant rejection by suppressing immune response
  • Used after liver, kidney, heart, and other organ transplants
  • Must be taken long-term as prescribed by your doctor
  • Should not be stopped without medical consultation

Therapeutic Uses

  • Prevention of organ transplant rejection in liver, kidney, heart, and other organ recipients
  • Control and suppression of immune response following transplantation

How it Works

Advagraf 0.5mg works by targeting cells in your immune system called T-lymphocytes, which would normally attack a transplanted organ. The medication binds to a protein called FKBP-12 and forms a complex that blocks calcineurin phosphatase activity. This action prevents T-cells from being activated and multiplying, effectively reducing your immune system's ability to reject the transplanted organ while still allowing your body to fight infections.

How to Take

Your doctor will determine the exact dose and duration of treatment based on your transplant type, overall health, and other medications. Always follow your doctor's instructions precisely, as proper dosing is critical for transplant success.

Instructions

  • Swallow the capsule whole with a glass of water—do not open, break, crush, or chew it
  • Take Advagraf on an empty stomach for best absorption
  • If taking with meals, wait at least 1 hour before or 2-3 hours after eating
  • Take at the same time each day to maintain consistent medication levels
  • Do not alter your dose without consulting your doctor

Timing

On an empty stomach (at least 1 hour before meals or 2-3 hours after meals)

Missed dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.

Overdose

If you suspect an overdose, seek immediate emergency medical attention or call your poison control center right away.

Side Effects

  • Tremors, headache, dizziness, or confusion
  • Nausea, vomiting, diarrhea, or constipation
  • Hair loss, itchy skin, or swelling in arms and legs
  • Increased or decreased heartbeat, or severe kidney problems
  • Fever, unusual bruising, yellowing of skin or eyes, or vision changes
  • Seizures, breathing problems, or coughing

Safety Advice

Pregnancy

Consult Doctor

Animal studies have shown that Advagraf may cause harm to an unborn baby. However, the benefits of preventing organ rejection may outweigh the risks in some pregnant transplant recipients.

Tip: Inform your doctor immediately if you are pregnant, think you may be pregnant, or are planning to become pregnant. Do not stop taking Advagraf without medical guidance, as stopping may cause transplant rejection.

Breastfeeding

Unsafe

Advagraf passes into breast milk and may cause harmful effects in nursing infants.

Tip: Do not breastfeed while taking Advagraf 0.5mg Capsule. Discuss alternative feeding methods with your doctor.

Liver Disease

Consult Doctor

Advagraf is processed by the liver. Severe liver disease can affect how your body handles this medication.

Tip: Inform your doctor if you have liver problems before starting treatment. Dose adjustments may be necessary if you have severe liver disease.

Kidney Disease

Consult Doctor

Advagraf can affect kidney function and requires careful monitoring in patients with kidney problems.

Tip: Inform your doctor of any kidney issues before starting treatment. Regular kidney function tests will be necessary during therapy.

Lung Disease

Consult Doctor

The safety and effectiveness of Advagraf in patients with existing lung disorders are not well established.

Tip: Consult your doctor before starting Advagraf if you have any lung conditions such as asthma or chronic obstructive pulmonary disease (COPD).

Alcohol

Unsafe

Alcohol can increase the risk of liver problems and excessive drowsiness when combined with Advagraf.

Tip: Avoid consuming alcohol while taking this medication.

Driving & Operating Machinery

Unsafe

Advagraf may cause drowsiness, dizziness, confusion, and vision problems that impair your ability to drive or operate machinery safely.

Tip: Do not drive vehicles or operate heavy machinery until you know how this medication affects you. Avoid these activities if you experience any vision changes or drowsiness.

FAQs

What if I missed a dose of Advagraf Capsule?
Take the missed dose as soon as you remember. However, if your next scheduled dose is approaching, skip the missed dose entirely and resume your normal dosing schedule. Never take two doses together or double up on doses to compensate for a missed one, as this increases the risk of side effects and toxicity.
What should you not use with Advagraf Capsule?
Avoid taking medications containing mycophenolic acid, nelfinavir, sirolimus, and cyclosporine alongside Advagraf without your doctor's approval. Certain antibiotics and antiviral drugs may also interact with this medication. Always inform your healthcare provider about all prescription medications, over-the-counter drugs, vitamins, supplements, and herbal products you use before starting Advagraf treatment.
What is the recommended duration for taking Advagraf Capsule after a transplant?
Advagraf must be taken long-term, typically for life, to prevent your body from rejecting the transplanted organ. Your doctor will determine the appropriate duration based on your individual transplant situation. Do not stop taking this medication without consulting your doctor, as discontinuing Advagraf can lead to transplant rejection and loss of your organ.
Can Advagraf Capsule increase the risk of infections?
Yes, because Advagraf suppresses your immune system to prevent organ rejection, it can increase your susceptibility to infections, including serious bacterial, viral, and fungal infections. Report any signs of infection such as fever, unusual tiredness, or persistent cough to your doctor immediately. Inform your doctor before receiving any vaccinations, as they may not be effective while taking Advagraf.
Can Advagraf Capsule affect kidney function?
Advagraf can impact kidney function, and long-term use may increase the risk of kidney problems. Your doctor will regularly monitor your kidney function through blood tests. Inform your doctor immediately if you notice reduced urine output, changes in urination patterns, or swelling in your legs. Maintaining proper hydration and following your doctor's monitoring schedule is essential.
Should I follow any dietary restrictions while taking Advagraf Capsule?
Yes, you must avoid grapefruit and grapefruit juice entirely, as they significantly increase Advagraf levels in your blood and raise the risk of serious side effects. Additionally, take Advagraf on an empty stomach (1 hour before or 2-3 hours after meals) for optimal absorption. Avoid alcohol while taking this medication. For specific dietary guidance tailored to your transplant protocol, consult your healthcare provider.

Drug Interactions

Several medications and foods can interact with Advagraf, affecting how well it works or increasing the risk of side effects. It is crucial to inform your healthcare provider about all medications you take, including prescription drugs, over-the-counter products, vitamins, supplements, and herbal remedies before starting Advagraf treatment.

Major interactions

  • Grapefruit and grapefruit juice—can increase Advagraf levels in your blood
  • Mycophenolic acid-containing products
  • Nelfinavir (antiviral medication)
  • Sirolimus (another immunosuppressant)
  • Cyclosporine (another immunosuppressant)
  • Certain antibiotics and antiviral medications

Precautions

  • Always inform your doctor about all medications before starting Advagraf
  • Consult your doctor before receiving any vaccinations
  • Avoid alcohol while taking this medication
  • Inform your doctor if you experience diarrhea lasting more than one day, as this can affect medication absorption

Important

Do not consume grapefruit or grapefruit juice while taking Advagraf 0.5mg Capsule, as this can significantly increase medication levels in your blood and raise the risk of side effects.

Storage Details

🌡 Store at room temperature (25°C)

Keep in a cool, dry place away from direct sunlight and moisture

  • Keep capsules away from reach of children and pets
  • Store in original packaging to protect from light and moisture
  • Do not store in bathrooms or humid areas

Fact Box

Active Ingredient
Tacrolimus 0.5mg
Drug Class
Calcineurin Inhibitor (Immunosuppressant)
Therapeutic Use
Prevention of organ transplant rejection
Prescription Required
Yes

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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