₹16,526.20 ₹21,801.77 (You Save ₹5,276)

Sourced from: PFIZER LTD
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₹16,526.20 MRP: ₹21,801.77 24% OFF

Inclusive of all taxes

₹16,526.20/Unit
Rx Prescription Required ❄️ Cold Chain
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PFIZER LTD
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Quick overview

Atgam 250mg Injection contains ANTITHYMOCYTE IMMUNOGLOBULINS and is marketed by PFIZER LTD. Country of origin: United States of America. This pack is , priced at ₹16,526.20 inclusive of all taxes (about 24% off MRP). A valid prescription is required to order this medicine. This product needs cold-chain storage and handling. On MedsRight, Atgam 250mg Injection is organised under the Others speciality and the Transplant condition category.

Know about Atgam 250mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: ANTITHYMOCYTE IMMUNOGLOBULINS — that is what goes into Atgam 250mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹16,526.20 for , including all taxes. The MRP printed on the pack is ₹21,801.77 — you save roughly 24% versus that.

  • Per-unit value: Roughly ₹16,526.20 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Atgam 250mg Injection under “Others” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Transplant” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: PFIZER LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is United States of America.

  • Prescription: You will need a valid prescription to buy Atgam 250mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep the cold chain: store and carry it the way the strip, carton, and leaflet say, especially if it must stay chilled.

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Atgam 250mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Atgam 250mg Injection contains antithymocyte immunoglobulins, a purified immune protein derived from horse plasma that has been specially treated to help your body's immune system. This medication works by suppressing an overactive immune response, making it essential for patients who have received organ transplants or suffer from certain blood disorders. Atgam is administered intravenously in a hospital or clinical setting under close medical supervision.

This injection is primarily used to prevent the body from rejecting a transplanted organ and to treat severe aplastic anemia, a condition where the bone marrow fails to produce enough blood cells. By modulating your immune system, Atgam helps reduce harmful immune attacks on transplanted organs or your own bone marrow cells, allowing better graft survival and restoration of normal blood cell production.

Your healthcare provider will determine the appropriate dosage and treatment schedule based on your specific condition, body weight, and response to therapy. Always inform your doctor about all medications you are taking, as certain drugs may interact with Atgam 250mg Injection.

Key points

  • Purified immunoglobulin derived from hyperimmunized horse plasma
  • Suppresses T lymphocytes to prevent organ rejection and treat immune-mediated blood disorders
  • Administered as intravenous infusion in hospital settings only
  • Reduces need for high-dose corticosteroids and their associated side effects

Therapeutic Uses

  • Prevention of organ rejection following kidney transplantation and other solid organ transplants
  • Treatment of severe aplastic anemia by restoring normal blood cell production
  • Management of acute renal allograft rejection in kidney transplant recipients
  • Treatment of autoimmune hemolytic anemia and other immune-mediated blood disorders
  • Supportive therapy for myasthenia gravis and graft-versus-host disease (GVHD)

How it Works

Atgam 250mg Injection works by targeting and depleting T lymphocytes, which are immune cells responsible for organ rejection and autoimmune attacks. In transplant patients, this suppression of the immune response prevents the body from recognizing and attacking the transplanted organ as foreign tissue, thereby improving transplant success and graft survival rates. For patients with aplastic anemia, reducing these immune cells stops the body's damaging attack on bone marrow cells, allowing normal blood cell production to resume. This dual action—preventing rejection while reducing harmful immune-mediated cell destruction—makes Atgam an important tool in managing both transplant complications and severe blood disorders.

How to Take

Atgam 250mg Injection is administered exclusively as an intravenous infusion in a hospital or clinical environment. Your healthcare team will calculate your exact dose based on your condition, body weight, and treatment response. The injection is never given by mouth or through self-injection at home.

Instructions

  • Receive injection only in a hospital or authorized clinical setting
  • Allow healthcare staff to verify your identity and confirm the correct medication
  • Report any allergies or previous adverse reactions before administration
  • Remain at the facility for observation after infusion is complete
  • Keep all follow-up appointments for ongoing monitoring and dose adjustments

Timing

Atgam is administered on a schedule determined by your physician, typically during hospital stays or scheduled clinical visits. Do not attempt to adjust timing without medical guidance.

Missed dose

Since Atgam is administered in a medical setting, doses are not missed in the traditional sense. If a scheduled infusion cannot occur as planned, contact your healthcare provider immediately to reschedule your appointment.

Overdose

Overdose with Atgam 250mg Injection is unlikely in clinical settings due to controlled administration. However, if overdose is suspected, seek immediate emergency medical attention at the nearest hospital.

Side Effects

  • Fever, chills, and body aches during or shortly after infusion
  • Dizziness, lightheadedness, or weakness affecting daily activities
  • Nausea, vomiting, or abdominal discomfort following injection
  • Increased susceptibility to infections due to immune system suppression
  • Skin rashes, hives, or localized swelling at or near the injection site
  • Headache or joint and muscle pain in the days following treatment

Safety Advice

Pregnancy

Consult Doctor

Limited safety data exists for Atgam 250mg Injection use during pregnancy. The potential risks and benefits must be carefully evaluated by your obstetrician and transplant specialist.

Tip: Discuss your pregnancy status or plans to become pregnant with your doctor before starting treatment. Do not stop taking Atgam suddenly if you become pregnant.

Breastfeeding

Consult Doctor

It is unknown whether Atgam 250mg Injection passes into breast milk or could harm a nursing infant. Your specific situation requires careful evaluation.

Tip: Inform your healthcare provider if you are breastfeeding. Your doctor will help determine whether breastfeeding is safe during Atgam therapy.

Liver Disease

Consult Doctor

Atgam is primarily metabolized in the liver. If you have liver impairment or pre-existing liver disease, the medication may accumulate in your body, affecting how well it works and potentially causing toxicity.

Tip: Inform your doctor of any liver disease or liver function problems before starting treatment. Your liver function may need to be monitored during therapy.

Kidney Disease

Consult Doctor

Kidney function status may affect how your body processes and eliminates Atgam 250mg Injection. Patients with severe kidney impairment may require special monitoring.

Tip: Report any kidney disease or kidney problems to your healthcare provider before treatment begins. Kidney function tests may be recommended during therapy.

Lung Disease

Consult Doctor

Safety of Atgam 250mg Injection in patients with pre-existing lung diseases has not been established. Your condition requires individual assessment.

Tip: Disclose any respiratory or lung conditions to your doctor before starting Atgam therapy. Close monitoring may be necessary during treatment.

Alcohol

Unsafe

Alcohol consumption while taking Atgam 250mg Injection is unsafe. Alcohol may reduce the medication's effectiveness and increase the risk of toxic side effects, potentially harming your liver and overall health.

Tip: Avoid alcohol entirely during your Atgam treatment. If you have questions about specific beverages or products, ask your healthcare provider.

Driving

Consult Doctor

Atgam 250mg Injection can cause dizziness and other side effects that may impair your ability to drive safely. Your individual response to the medication determines your specific risk.

Tip: Avoid driving and operating heavy machinery until you understand how Atgam affects you. If dizziness or weakness occurs, do not drive. Plan for transportation to and from your infusion appointments.

Active Infection

Unsafe

Atgam suppresses your immune system, which your body needs to fight infections. Starting treatment during active, severe, or systemic infections significantly increases the risk of serious complications.

Tip: Inform your doctor if you have any active infection before treatment begins. Treatment should be delayed until your infection is adequately treated and resolved.

Allergies

Unsafe

Individuals with known hypersensitivity to Atgam 250mg Injection, antithymocyte immunoglobulins, or any component of the medication should not receive it. Prior severe allergic reactions are absolute contraindications.

Tip: Report all known allergies to your healthcare provider before receiving any dose. Ensure your medical record clearly documents any previous allergic reactions to this or similar medications.

FAQs

How can I minimize the risk of infections while on Atgam 250mg Injection therapy?
Since Atgam 250mg Injection suppresses your immune system, infection prevention is critical. Maintain excellent personal hygiene by washing your hands frequently with soap and water, especially before eating and after using the bathroom. Avoid close contact with people who are sick, and stay away from large crowds when possible. Ask your doctor before receiving any vaccines during treatment, as live vaccines are unsafe. Keep all medical appointments for monitoring, and report fever, cough, unusual tiredness, or other signs of infection to your healthcare provider immediately. Following these precautions significantly reduces your infection risk during Atgam therapy.
Can Atgam 250mg Injection cause long-term kidney or liver damage?
While Atgam 250mg Injection is primarily metabolized by the liver, long-term kidney or liver damage is not commonly reported when the medication is used appropriately under medical supervision. However, patients with pre-existing liver or kidney disease may be at higher risk and require careful monitoring. Your healthcare provider will likely order blood tests before starting treatment and periodically during therapy to monitor liver and kidney function. If you have concerns about your liver or kidney health, discuss them with your doctor, who may adjust your treatment plan or increase monitoring frequency to ensure your safety.
What steps can be taken to minimize infusion-related reactions?
Infusion-related reactions such as fever, chills, and body aches are common with Atgam 250mg Injection but can be minimized through several strategies. Your healthcare team may premedicate you with acetaminophen, antihistamines, or corticosteroids before infusion to reduce reaction severity. Administering the medication slowly and allowing time for your body to adjust helps many patients tolerate it better. Staying well-hydrated before and after infusion supports your body's response to the medication. Inform your medical team if you experienced reactions to previous doses—they can adjust your premedication regimen or infusion rate accordingly. Most infusion reactions are manageable and typically become less severe with subsequent doses as your body adapts to the medication.
Is there an increased risk of developing malignancies with long-term Atgam 250mg Injection use?
Long-term use of immunosuppressive medications, including Atgam 250mg Injection, may slightly increase the risk of certain malignancies, particularly lymphomas and skin cancers. This increased risk is related to the overall immunosuppression that occurs with these medications rather than Atgam specifically. However, the benefits of preventing organ rejection or treating severe aplastic anemia often outweigh this risk for most patients. Your healthcare provider will weigh the benefits and risks specific to your condition. Regular monitoring, including skin checks and appropriate cancer screening, is recommended during and after long-term Atgam therapy to detect any changes early. Discuss your individual cancer risk with your transplant or hematology specialist.
Can Atgam 250mg Injection increase the risk of viral infections other than cytomegalovirus (CMV)?
Yes, because Atgam 250mg Injection suppresses T lymphocytes, your immune system's ability to fight various viral infections is reduced. While cytomegalovirus is a well-known concern, patients on Atgam therapy are also at increased risk for other viral infections, including herpes simplex virus, varicella-zoster virus (shingles), Epstein-Barr virus, and respiratory viruses. Your doctor may recommend antiviral medications as preventive therapy during your treatment. Maintaining good hygiene, avoiding sick contacts, and reporting symptoms like unusual fatigue, fever, or skin rashes promptly helps protect you. Regular monitoring allows your healthcare team to detect and treat viral infections early, before they become serious complications.
Are any specific tests or monitoring required for Atgam 250mg Injection therapy patients?
Yes, regular monitoring is essential for all patients receiving Atgam 250mg Injection therapy. Before starting treatment, your doctor will perform baseline blood tests including complete blood count (CBC) and liver and kidney function tests (LFTs). During therapy, you will need periodic blood work to monitor how your bone marrow is responding, especially important for aplastic anemia patients. Liver and kidney function will be checked at regular intervals since Atgam is metabolized by the liver. Your doctor may also monitor your immune function and screen for infections or viral reactivation. For transplant patients, monitoring of graft function and rejection markers is important. Attend all scheduled appointments and laboratory tests—these monitoring results help your doctor adjust your treatment and catch any complications early.

Drug Interactions

Atgam 250mg Injection may interact with other medications, potentially reducing effectiveness or causing unwanted side effects. It is crucial to inform your healthcare provider about all medicines you take, including prescription drugs, over-the-counter medications, dietary supplements, vitamins, and herbal products before starting treatment.

Major interactions

  • Live vaccines should be avoided during Atgam therapy as the medication suppresses immune function
  • Other immunosuppressive medications may increase infection risk when combined with Atgam

Precautions

  • Inform your doctor if you have active infections before starting treatment
  • Allow adequate time between Atgam and live vaccinations—consult your doctor about timing
  • Monitor for signs of infection more carefully when taking multiple immune-suppressing medications
  • Review all supplements and herbal products with your healthcare provider before treatment begins

Important

Never start, stop, or change any medication without consulting your healthcare provider. Some combinations with Atgam 250mg Injection may be unsafe or require dose adjustments.

Storage Details

🌡 Store between 2°C and 8°C (36°F to 46°F) in a standard refrigerator

Keep in a safe place, away from direct light and excessive moisture

  • Store in the original packaging to protect from light exposure
  • Keep out of reach of children and pets
  • Do not freeze the medication
  • Check expiration date before each use
  • If stored outside refrigerated conditions, consult your pharmacist about usability

Fact Box

Active Ingredient
Antithymocyte Immunoglobulins (purified immune protein from hyperimmunized horse plasma)
Drug Class
Immunosuppressant / Antilymphocyte Globulin
Therapeutic Use
Prevention of organ transplant rejection; treatment of aplastic anemia, allograft rejection, and immune-mediated blood disorders
Route of Administration
Intravenous infusion only, in hospital or clinical setting
Prescription Required
Yes
Storage Temperature
Refrigerated: 2°C to 8°C (36°F to 46°F)

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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