Biovorin 50mg Injection

LEUCOVORIN CALCIUM
₹228.00 ₹520.00 (You Save ₹292)

1 Vial(s) Of 5ml

Sourced from: ZYDUS CADILA
56% OFF
★★★★★ 4.8 On Google
₹228.00 MRP: ₹520.00 56% OFF

Inclusive of all taxes

1 Vial(s) Of 5ml
₹228.00/Unit
Rx Prescription Required ❄️ Cold Chain
Salt Composition
LEUCOVORIN CALCIUM
Marketer
ZYDUS CADILA
🚚
Dispatch: Tomorrow
if Order in: --h --m --s

Quick overview

Biovorin 50mg Injection contains LEUCOVORIN CALCIUM and is marketed by ZYDUS CADILA. Country of origin: India. This pack is 1 Vial(s) Of 5ml, priced at ₹228.00 inclusive of all taxes (about 56% off MRP). A valid prescription is required to order this medicine. This product needs cold-chain storage and handling. On MedsRight, Biovorin 50mg Injection is organised under the Oncology speciality and the Anti Cancer condition category.

Know about Biovorin 50mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: LEUCOVORIN CALCIUM — that is what goes into Biovorin 50mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹228.00 for 1 Vial(s) Of 5ml, including all taxes. The MRP printed on the pack is ₹520.00 — you save roughly 56% versus that.

  • Per-unit value: Roughly ₹228.00 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Biovorin 50mg Injection under “Oncology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Anti Cancer” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: ZYDUS CADILA is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Biovorin 50mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep the cold chain: store and carry it the way the strip, carton, and leaflet say, especially if it must stay chilled.

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Biovorin 50mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Biovorin 50mg Injection contains leucovorin calcium, a folic acid analog that works by replenishing folic acid levels in your body. This medication is commonly used to protect your body from the harmful side effects of methotrexate, a powerful chemotherapy drug used to treat various cancers. Biovorin is also given as an emergency treatment if someone has taken too much methotrexate. Additionally, it is used alongside other cancer medications to treat colorectal cancer and to address anemia caused by folic acid deficiency.

Your doctor or trained nurse will administer Biovorin as an injection directly into your vein or muscle, depending on your specific condition. The timing and dosage will be carefully determined based on your medical needs and the severity of your condition.

Key points

  • Protects against methotrexate toxicity and harmful side effects
  • Used to treat methotrexate overdose
  • Enhances colorectal cancer treatment when combined with 5-fluorouracil
  • Treats folic acid deficiency anemia by replenishing red blood cell formation

Therapeutic Uses

  • Prevention of harmful effects from methotrexate chemotherapy
  • Treatment of methotrexate overdose and toxicity
  • Support for colorectal cancer treatment in combination with other anticancer medications
  • Treatment of anemia caused by low folic acid levels

How it Works

Biovorin 50mg Injection works by counteracting the effects of folic acid antagonists like methotrexate. It bypasses the enzyme that methotrexate blocks, allowing your body to obtain the folic acid needed for healthy cell function. For colorectal cancer treatment, Biovorin enhances the effectiveness of 5-fluorouracil by improving how cancer cells respond to this chemotherapy drug. In cases of anemia, Biovorin directly supplies the folic acid your body needs to produce healthy red blood cells.

How to Take

Biovorin 50mg Injection must be administered by a qualified healthcare professional, typically a trained physician or nurse experienced in cancer chemotherapy. The injection is given either intravenously (into a vein) or intramuscularly (into a muscle) based on your condition.

Instructions

  • Receive the injection from a qualified healthcare professional in a clinical setting
  • When used with methotrexate, Biovorin is typically administered 24 hours after the methotrexate dose to avoid interfering with its therapeutic effects
  • In cases of methotrexate overdose, Biovorin should be given as soon as possible
  • Your doctor will determine the exact dose and treatment duration based on your medical condition and severity

Timing

Timing depends on your specific treatment protocol. For methotrexate protection, it is typically given 24 hours after methotrexate administration. Your healthcare team will provide a specific schedule.

Missed dose

If you miss a scheduled dose, inform your healthcare provider immediately. Your doctor will reschedule your next dose and adjust your treatment plan as needed.

Overdose

If you have accidentally received too much Biovorin 50mg Injection, contact your doctor or seek emergency medical care right away. Do not attempt to manage an overdose on your own.

Side Effects

  • Diarrhea
  • Nausea and vomiting
  • Inflamed and sore mouth
  • Tiredness and fatigue
  • Allergic reactions including rash, wheezing, shortness of breath, and facial swelling

Safety Advice

Pregnancy

Consult Doctor

Limited research is available on the safety of Biovorin 50mg Injection during pregnancy. It is unclear whether this medication can safely be used by pregnant women.

Tip: If you are pregnant, suspect you may be pregnant, or are planning to become pregnant, inform your doctor before treatment begins. Your doctor will assess the risks and benefits for your specific situation.

Breastfeeding

Consult Doctor

Limited information exists regarding the safety of Biovorin 50mg Injection while breastfeeding. It is unknown whether this medication passes into breast milk.

Tip: If you are breastfeeding or planning to breastfeed, consult your doctor before using this medication. Your doctor can provide guidance based on your individual circumstances.

Liver Disease

Consult Doctor

The safety of Biovorin 50mg Injection in patients with liver disorders is not well established. Your liver plays a role in processing medications, so liver problems may affect how your body handles this drug.

Tip: Inform your doctor if you have any liver disease or liver function abnormalities before starting treatment.

Kidney Disease

Consult Doctor

If you have kidney problems, inform your healthcare provider before receiving Biovorin, as kidney function may affect how your body processes this medication.

Tip: Discuss your kidney health with your doctor to ensure Biovorin is appropriate for you.

Heart Disease

Consult Doctor

Patients with existing heart problems should inform their doctor before receiving Biovorin 50mg Injection.

Tip: Disclose any heart conditions to your healthcare provider prior to treatment.

Lung Disease

Consult Doctor

The safety of Biovorin 50mg Injection in patients with lung disorders has not been clearly established. Lung problems should be discussed with your doctor.

Tip: If you have any lung disease or respiratory condition, inform your doctor before starting treatment.

Allergies

Unsafe

Do not take Biovorin 50mg Injection if you are allergic to leucovorin calcium, calcium folinate, or any other ingredients in this medicine. Allergic reactions can be serious.

Tip: If you experience symptoms such as wheezing, trouble breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue, seek immediate medical attention.

Alcohol

Consult Doctor

The safety of consuming alcohol while taking Biovorin 50mg Injection is unknown and has not been thoroughly studied.

Tip: Consult your doctor for specific advice about alcohol consumption during your treatment.

Driving

Safe

Biovorin 50mg Injection does not impair your ability to drive or operate heavy machinery.

Tip: You may safely drive and operate machinery while taking this medication.

FAQs

Why is Biovorin 50mg Injection given 24 hours after methotrexate?
Biovorin 50mg Injection is typically administered 24 hours after methotrexate to prevent interference with the chemotherapy drug's therapeutic effect on cancer cells. When given at the correct timing, Biovorin protects your healthy cells without reducing methotrexate's ability to fight cancer. However, in cases of methotrexate overdose, Biovorin should be administered as soon as possible to prevent serious harm.
Can Biovorin 50mg Injection cause swelling?
Yes, Biovorin 50mg Injection may cause allergic reactions in some people, including swelling of the face, throat, lips, and tongue. Other allergic symptoms can include rash, itching, hives, wheezing, and shortness of breath. If you experience any of these symptoms, seek immediate medical attention.
Can Biovorin 50mg Injection cause seizures?
There is no evidence that Biovorin 50mg Injection directly causes seizures. However, if you are taking seizure medication, Biovorin can affect how your seizure medication works in your body. It is important to inform your doctor about all medications you are taking, including seizure drugs, so your treatment can be properly monitored.
How long does it take for Biovorin 50mg Injection to work?
The onset of Biovorin's protective effects against methotrexate toxicity occurs relatively quickly when given at the appropriate 24-hour interval. For anemia treatment, improvement in folic acid levels and red blood cell production takes time and will be monitored through regular blood tests. Your doctor will conduct lab tests to check the effectiveness of the medication and adjust your treatment plan as needed.
What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Biovorin 50mg Injection?
To help your body excrete methotrexate efficiently while taking Biovorin, stay well-hydrated by drinking adequate fluids as directed by your doctor. Maintaining proper hydration supports kidney function and helps eliminate methotrexate from your body. Your healthcare team will monitor your kidney function and overall health during treatment. Follow all of your doctor's instructions regarding hydration, medication timing, and follow-up appointments to ensure the best outcomes.

Drug Interactions

Biovorin 50mg Injection may interact with other medications you are taking. It is crucial to inform your healthcare provider about all medicines you use, including prescription medications, over-the-counter drugs, vitamins, supplements, and herbal products. Some medications can reduce the effectiveness of Biovorin or cause unwanted side effects when used together.

Major interactions

  • Seizure medications — Biovorin may affect how these medications work in your body
  • Other folic acid antagonists or folate-dependent medications

Precautions

  • Always disclose all current medications to your doctor before starting treatment
  • Do not start, stop, or change any medications without consulting your healthcare provider
  • Inform your doctor if you are taking seizure medications, as these require special monitoring
  • Report any new symptoms or changes in your condition after starting Biovorin

Important

Do not take Biovorin 50mg Injection if you have certain types of anemia where vitamin B12 is deficient, such as pernicious anemia or megaloblastic anemia, without first consulting your doctor.

Storage Details

🌡 Store in a refrigerator between 2°C and 8°C (36°F and 46°F)

Keep in a cool, dark place away from direct light and heat

  • Store out of reach of children and pets
  • Do not freeze the medication
  • Keep the original packaging to protect from light exposure
  • Do not use if the solution appears discolored or contains particles

Fact Box

Active Ingredient
Leucovorin Calcium (Calcium Folinate)
Drug Class
Folic Acid Analog
Therapeutic Use
Methotrexate protection, methotrexate overdose treatment, colorectal cancer support, folic acid deficiency anemia
Prescription Required
Yes

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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