Darzalex 400mg Injection

DARATUMUMAB
₹54,710.50 ₹64,018.75 (You Save ₹9,308)

Sourced from: JOHNSON & JOHNSON PVT LTD
15% OFF
★★★★★ 4.8 On Google
₹54,710.50 MRP: ₹64,018.75 15% OFF

Inclusive of all taxes

₹54,710.50/Unit
Rx Prescription Required ❄️ Cold Chain
Salt Composition
DARATUMUMAB
🚚
Dispatch: Tomorrow
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Quick overview

Darzalex 400mg Injection contains DARATUMUMAB and is marketed by JOHNSON & JOHNSON PVT LTD. Country of origin: United States of America. This pack is , priced at ₹54,710.50 inclusive of all taxes (about 15% off MRP). A valid prescription is required to order this medicine. This product needs cold-chain storage and handling. On MedsRight, Darzalex 400mg Injection is organised under the Oncology speciality and the Anti Cancer condition category.

Know about Darzalex 400mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: DARATUMUMAB — that is what goes into Darzalex 400mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹54,710.50 for , including all taxes. The MRP printed on the pack is ₹64,018.75 — you save roughly 15% versus that.

  • Per-unit value: Roughly ₹54,710.50 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Darzalex 400mg Injection under “Oncology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Anti Cancer” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: JOHNSON & JOHNSON PVT LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is United States of America.

  • Prescription: You will need a valid prescription to buy Darzalex 400mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep the cold chain: store and carry it the way the strip, carton, and leaflet say, especially if it must stay chilled.

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Darzalex 400mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Darzalex 400mg Injection is a targeted cancer therapy used to treat multiple myeloma, a serious blood cancer affecting bone marrow cells. It contains daratumumab, a monoclonal antibody—a type of protein that specifically recognizes and attaches to cancer cells to help your immune system destroy them. This medication is prescribed for adults aged 18 and older with newly diagnosed or relapsed/refractory multiple myeloma. Darzalex 400mg works by binding to a protein called CD38 found on myeloma cell surfaces, triggering your body's natural defenses to attack and eliminate these cancer cells. It can be used alone or combined with other cancer treatments like chemotherapy, corticosteroids, or immunomodulatory drugs for enhanced effectiveness. Before starting treatment, inform your doctor about any history of hepatitis B infection, as this medicine may reactivate the virus. Also report any breathing problems, previous shingles infection, or if you're on a sodium-restricted diet, as this injection contains sodium.

Key points

  • Monoclonal antibody therapy targeting CD38 protein on multiple myeloma cells
  • Used for newly diagnosed and relapsed/refractory multiple myeloma in adults 18+
  • Can be used as monotherapy or combined with other cancer treatments
  • Administered by healthcare professionals as intravenous infusion only

Therapeutic Uses

  • Treatment of multiple myeloma (blood cancer of bone marrow)
  • Used alone or combined with chemotherapy, corticosteroids, or immunomodulatory agents
  • Slows disease progression and reduces tumor burden
  • Improves immune system function to attack cancer cells
  • Enhances overall survival rates in multiple myeloma patients

How it Works

Darzalex 400mg works by binding to CD38, a protein present on the surface of multiple myeloma cells. This binding activates your immune system to recognize and attack cancer cells, triggering their destruction through multiple mechanisms including antibody-dependent cellular cytotoxicity and direct cell death. By enhancing your body's natural cancer-fighting abilities, it helps slow disease progression and improve outcomes in multiple myeloma.

How to Take

Darzalex 400mg must be administered by a trained healthcare professional only—never self-inject. Your doctor will determine the appropriate dose and treatment duration based on disease severity, your overall health, and response to therapy. The medication is given as an intravenous (IV) infusion directly into your vein, and you'll be closely monitored during and after administration for any adverse reactions.

Instructions

  • Attend all scheduled infusion appointments at your healthcare facility
  • Allow your doctor or nurse to administer the injection via IV infusion
  • Remain under medical supervision during the infusion process
  • Report any infusion-related reactions immediately (facial swelling, difficulty breathing, throat tightness)
  • Inform your healthcare team of all medications and supplements you're taking

Timing

As determined by your oncologist based on your treatment protocol

Missed dose

If you miss a scheduled infusion appointment, contact your doctor immediately to reschedule. Do not attempt to make up doses on your own.

Overdose

Darzalex 400mg is administered only in controlled medical settings under professional supervision, making overdose unlikely. If you experience severe infusion reactions, your healthcare team may slow or stop the infusion and provide supportive care.

Side Effects

  • Infusion-related reactions including swelling of face, lips, mouth, tongue, or throat
  • Decreased white blood cell count, which may increase infection risk
  • Reduced platelet count, which may increase bleeding or bruising tendency
  • Fatigue and general weakness during treatment
  • Infusion site reactions such as pain, redness, or swelling at injection site

Safety Advice

Pregnancy

Consult Doctor

The safety of Darzalex 400mg during pregnancy has not been established. Animal studies have not been completed, and potential risks to the developing fetus are unknown.

Tip: Inform your doctor immediately if you are pregnant or planning pregnancy. Effective contraception is essential during treatment and for three months after treatment ends.

Breastfeeding

Consult Doctor

It is unknown whether Darzalex 400mg passes into breast milk or if it could harm a nursing infant. Safety in breastfeeding patients has not been established.

Tip: Consult your doctor before starting treatment if you are breastfeeding. Your doctor will help determine the safest option for you and your baby.

Liver Function

Consult Doctor

Safety in patients with liver disease has not been thoroughly studied. Darzalex 400mg may be processed differently in patients with impaired liver function.

Tip: Inform your doctor of any liver disease or liver-related symptoms before starting treatment. Report any signs of liver problems such as jaundice, dark urine, or persistent abdominal pain.

Kidney Function

Consult Doctor

Safety in patients with kidney disease requires careful evaluation. Your doctor may need to monitor kidney function during treatment.

Tip: Disclose any kidney problems or history of kidney disease to your healthcare provider before treatment begins.

Respiratory Conditions

Consult Doctor

Patients with a history of asthma or chronic obstructive pulmonary disease (COPD) may be at higher risk for infusion-related respiratory complications.

Tip: Inform your doctor if you have breathing problems, asthma, or COPD before receiving Darzalex 400mg. Close monitoring during infusion is important.

Hepatitis B History

Consult Doctor

Darzalex 400mg may cause hepatitis B virus to become active again in patients with a history of hepatitis B infection, potentially leading to serious liver disease.

Tip: Disclose any history of hepatitis B infection to your doctor before treatment. Your doctor may order blood tests and may prescribe antiviral medication to prevent reactivation.

Shingles History

Consult Doctor

Patients who have had shingles (herpes zoster) in the past should inform their doctor, as Darzalex 400mg may affect immune function.

Tip: Report any previous shingles infection to your healthcare provider before starting treatment.

Alcohol Consumption

Consult Doctor

The safety of alcohol consumption during Darzalex 400mg treatment has not been established. Alcohol may interact with the medication or increase certain side effects.

Tip: Consult your doctor about alcohol use during treatment. Your doctor will provide personalized guidance based on your specific situation.

Blood Transfusions

Consult Doctor

Darzalex 400mg can change blood test results used to determine your blood type, which may complicate blood transfusions.

Tip: Always inform healthcare providers administering blood transfusions that you are being treated with Darzalex 400mg. Provide documentation of your actual blood type to ensure safe transfusion.

Sodium Intake

Consult Doctor

This injection contains sodium. Patients on sodium-restricted diets need to be aware of this when receiving treatment.

Tip: Inform your doctor if you follow a salt-controlled diet. The sodium content should be considered as part of your overall daily intake.

FAQs

Is Darzalex 400mg chemotherapy medicine?
No, Darzalex 400mg is not traditional chemotherapy. It is a targeted cancer therapy known as a monoclonal antibody. While chemotherapy works by killing rapidly dividing cells, Darzalex 400mg specifically targets CD38 protein on multiple myeloma cells and works by enhancing your immune system to recognize and destroy cancer cells. It can be used alongside chemotherapy or other treatments for improved efficacy.
What is the recommended frequency for receiving Darzalex 400mg treatments?
The treatment schedule for Darzalex 400mg depends on your specific condition, disease stage, and response to therapy. Your oncologist will determine the dosing frequency and duration based on whether you have newly diagnosed or relapsed/refractory multiple myeloma, and whether it's being used as monotherapy or combined with other drugs. Some patients receive weekly infusions initially, then less frequently as treatment progresses. Your doctor will provide a personalized schedule.
Does Darzalex 400mg cure cancer?
Darzalex 400mg is used to treat multiple myeloma and help control the disease, but it is not considered a cure. It works by slowing disease progression, reducing tumor burden, and improving survival rates. Many patients achieve remission or long-term disease control with this treatment, but multiple myeloma typically requires ongoing management. Your doctor will discuss realistic treatment goals and what to expect with your individual case.
Do I need to maintain any diet during the treatment with Darzalex 400mg?
There is no specific diet required during Darzalex 400mg treatment. However, maintaining good overall nutrition supports your immune system and treatment tolerance. If you are on a sodium-restricted diet, inform your doctor since this injection contains sodium. Your healthcare team may recommend eating well-balanced meals, staying hydrated, and avoiding foods that increase infection risk if your white blood cell count drops. Ask your doctor or nutritionist for personalized dietary advice.
I had a history of hepatitis B virus. Should I inform it before taking the Darzalex 400mg?
Yes, it is absolutely essential to inform your doctor about any history of hepatitis B infection before starting Darzalex 400mg. This medication can cause hepatitis B virus to reactivate in patients with prior infection, potentially leading to serious liver disease. Your doctor will likely order blood tests to check for hepatitis B and may prescribe antiviral medication to prevent reactivation during treatment. Do not start Darzalex 400mg without discussing your hepatitis B history with your oncologist.

Drug Interactions

Inform your healthcare provider about all medicines you take, including prescription drugs, over-the-counter medications, supplements, and herbal products. Certain medications may interact with Darzalex 400mg and reduce its effectiveness or increase side effects.

Major interactions

  • Blood pressure medications and heart condition treatments
  • Other chemotherapy or cancer treatment drugs
  • Immunomodulatory agents used in myeloma therapy

Precautions

  • Always disclose complete medication history to your oncologist
  • Report use of herbal products and dietary supplements
  • Inform about any recent vaccinations or planned immunizations
  • Let your doctor know if taking medications that affect immune function

Important

Do not start, stop, or change any medications without consulting your oncologist, as this may affect Darzalex 400mg effectiveness or safety.

Storage Details

🌡 Refrigerate between 2°C to 8°C (36°F to 46°F)

Store in original packaging away from light, heat, and moisture. Keep out of reach of children and pets.

  • Do not freeze the injection
  • Do not remove from refrigeration until ready for administration
  • Keep vials in original carton to protect from light
  • Check expiration date before each use

Fact Box

Active Ingredient
Daratumumab 400mg
Drug Class
Monoclonal Antibody
Therapeutic Use
Treatment of Multiple Myeloma
Route of Administration
Intravenous (IV) Infusion
Prescription Required
Yes
Storage Temperature
2°C to 8°C (Refrigerated)

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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