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Carefully Packed
Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.
1 Tube(s) Of 10gm
Inclusive of all taxes
Inclusive of all taxes
Topgraf 0.03% Ointment 10gm contains TACROLIMUS and is marketed by GLAXO SMITHKLINE PHARMACEUTICALS LTD. Country of origin: India. This pack is 1 Tube(s) Of 10gm, priced at ₹139.65 inclusive of all taxes (about 14% off MRP). A valid prescription is required to order this medicine. On MedsRight, Topgraf 0.03% Ointment 10gm is organised under the Infectious Disease speciality and the Transplant condition category.
From salt and price to delivery — the essentials in one short read, in about 30 seconds time.
Salt composition: TACROLIMUS — that is what goes into Topgraf 0.03% Ointment 10gm as the active part of the medicine. more options with same salt
Pack & price: You pay ₹139.65 for 1 Tube(s) Of 10gm, including all taxes. The MRP printed on the pack is ₹162.28 — you save roughly 14% versus that.
Per-unit value: Roughly ₹139.65 per unit — handy when you want to compare this pack with a bigger or smaller one.
Medical speciality: MedsRight files Topgraf 0.03% Ointment 10gm under “Infectious Disease” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality
Condition category: We link it to “Transplant” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition
Marketer: GLAXO SMITHKLINE PHARMACEUTICALS LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.
Country of origin: Country of origin for this pack is India.
Prescription: You will need a valid prescription to buy Topgraf 0.03% Ointment 10gm. Take it only the way your doctor told you.
Storage & handling: Keep it like any everyday medicine at room temperature, unless the pack asks for something special (fridge, away from light, etc.).
Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).
Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.
Availability: It should be possible to add Topgraf 0.03% Ointment 10gm to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.
Topgraf 0.03% Ointment contains tacrolimus, a powerful immunosuppressant medication that helps prevent your body from rejecting a transplanted organ. It belongs to a class of drugs called calcineurin inhibitors, which work by reducing your immune system's activity so it accepts the new organ instead of attacking it. Topgraf is commonly prescribed after liver, kidney, heart, and other organ transplants to help ensure long-term transplant success.
This medication is essential for transplant recipients as it significantly reduces the risk of organ rejection. However, because it affects your immune system, it requires careful monitoring and must be taken exactly as prescribed by your doctor. It is important to understand how to use this medication safely and what precautions to take while using it.
Key points
Topgraf works by attaching to a protein in your body called FKBP-12, creating a complex that blocks an important immune messenger called calcineurin. By blocking this messenger, the medication prevents T-lymphocytes (immune cells) from activating and multiplying, which significantly reduces your immune system's ability to attack the transplanted organ. This controlled reduction in immune activity allows your body to accept and integrate the new organ without rejecting it.
Your doctor will determine the exact dose and duration based on your transplant type, kidney function, and other individual factors. Always take Topgraf exactly as prescribed. It is important to maintain consistent dosing to prevent transplant rejection.
Instructions
Timing
Take on an empty stomach, at least 1 hour before meals or 2-3 hours after eating
Missed dose
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a forgotten dose.
Overdose
If you suspect an overdose, contact your healthcare provider or poison control center immediately. Do not attempt to treat overdose yourself.
Animal studies have shown that tacrolimus can cause harmful effects on the developing fetus. The safety of Topgraf during pregnancy has not been established in humans.
Tip: Inform your doctor immediately if you are pregnant, suspect you may be pregnant, or are planning to become pregnant before starting this medication. Discuss alternative options with your healthcare provider.
Topgraf passes into breast milk and may cause harmful effects on a nursing baby. The drug is not considered safe for breastfeeding mothers.
Tip: Do not breastfeed while taking Topgraf. Discuss feeding options with your doctor before starting treatment.
Patients with severe liver disease may require dose adjustments or careful monitoring as the liver plays a crucial role in metabolizing this medication.
Tip: Inform your doctor if you have a history of liver disease, hepatitis, or any liver problems. Your doctor may order liver function tests before and during treatment.
Topgraf can affect kidney function and may cause kidney injury in some patients. Your kidneys' health is particularly important while taking this medication.
Tip: Inform your doctor if you have any kidney disease or history of kidney problems. Regular kidney function tests will be necessary during treatment.
The safety and effectiveness of Topgraf in patients with lung diseases have not been fully established. More caution is needed in this population.
Tip: Consult your doctor if you have any lung disorders, asthma, or respiratory conditions before starting Topgraf.
Alcohol consumption while taking Topgraf can cause excessive drowsiness and may worsen liver problems, particularly in susceptible individuals.
Tip: Avoid all alcohol consumption while taking this medication. If you have questions about alcohol use, consult your doctor.
Topgraf may cause drowsiness, dizziness, and vision problems, which can impair your ability to safely drive or operate machinery.
Tip: Avoid driving or operating machinery until you know how this medication affects you. Consult your doctor if you experience these side effects.
Topgraf can interact with many medications, potentially reducing its effectiveness or increasing side effects. It is crucial to inform your doctor about all medications you take, including prescription drugs, over-the-counter medicines, supplements, vitamins, and herbal products, before starting treatment.
Major interactions
Precautions
Important
Consuming grapefruit or grapefruit juice while taking Topgraf is strictly prohibited as it can dangerously increase drug levels in your body.
🌡 Store at room temperature (25°C / 77°F)
Keep in a cool, dry place away from direct sunlight and moisture
Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.
Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.
Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.
We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.
This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.
You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.
Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.
MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.
We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.
Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.
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