Xmab 500mg Injection

RITUXIMAB
₹16,336.20 ₹39,992.34 (You Save ₹23,656)

1 Vial(s) Of 50ml

Sourced from: RPG LIFE SCIENCES LTD
59% OFF
★★★★★ 4.8 On Google
₹16,336.20 MRP: ₹39,992.34 59% OFF

Inclusive of all taxes

1 Vial(s) Of 50ml
₹16,336.20/Unit
Rx Prescription Required ❄️ Cold Chain
Salt Composition
RITUXIMAB
🚚
Dispatch: Tomorrow
if Order in: --h --m --s

Quick overview

Xmab 500mg Injection contains RITUXIMAB and is marketed by RPG LIFE SCIENCES LTD. Country of origin: India. This pack is 1 Vial(s) Of 50ml, priced at ₹16,336.20 inclusive of all taxes (about 59% off MRP). A valid prescription is required to order this medicine. This product needs cold-chain storage and handling. On MedsRight, Xmab 500mg Injection is organised under the Oncology speciality and the Anti Cancer condition category.

Know about Xmab 500mg Injection in 30 seconds

From salt and price to delivery — the essentials in one short read, in about 30 seconds time.

  • Salt composition: RITUXIMAB — that is what goes into Xmab 500mg Injection as the active part of the medicine. more options with same salt

  • Pack & price: You pay ₹16,336.20 for 1 Vial(s) Of 50ml, including all taxes. The MRP printed on the pack is ₹39,992.34 — you save roughly 59% versus that.

  • Per-unit value: Roughly ₹16,336.20 per unit — handy when you want to compare this pack with a bigger or smaller one.

  • Medical speciality: MedsRight files Xmab 500mg Injection under “Oncology” — the same kind of department-wise grouping you see in clinics and hospitals. Explore this speciality

  • Condition category: We link it to “Anti Cancer” so you can find it when you shop by health topic, not only by salt or brand. Browse this condition

  • Marketer: RPG LIFE SCIENCES LTD is the company behind this brand pack — the name you will usually see on invoices and packaging.

  • Country of origin: Country of origin for this pack is India.

  • Prescription: You will need a valid prescription to buy Xmab 500mg Injection. Take it only the way your doctor told you.

  • Storage & handling: Keep the cold chain: store and carry it the way the strip, carton, and leaflet say, especially if it must stay chilled.

  • Dispatch: We use Indian Standard Time. Order before 3:00 PM and your parcel is usually lined up to leave the warehouse the next working day (“Tomorrow”). After 3:00 PM, it slips to the following slot (“Day after”).

  • Doorstep delivery: After it leaves the warehouse, most addresses get it in about 3–4 days, depending on pincode and courier. Rural or remote areas can take a bit longer.

  • Availability: It should be possible to add Xmab 500mg Injection to your cart right now. Stock can run out if many people order at once, so finish checkout if you need it soon.

Detailed Information

Introduction

Xmab 500mg Injection is a monoclonal antibody medication containing rituximab, prescribed to treat a range of serious blood cancers and autoimmune conditions. This prescription injection works by targeting specific white blood cells, helping to slow or stop disease progression in adults and some children. Xmab is administered intravenously under medical supervision and is often combined with other medications for optimal therapeutic results.

This medication is used to treat non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis, vasculitis conditions affecting blood vessels, and pemphigus vulgaris. It belongs to a class of drugs called anti-CD20 monoclonal antibodies, which specifically target and destroy abnormal B-cells responsible for disease. Before starting Xmab, inform your doctor about any allergies, immune system disorders, infections, heart conditions, or hepatitis B history, as these factors may affect treatment safety.

Key points

  • Rituximab-based monoclonal antibody targeting B-lymphocytes
  • Treats blood cancers, rheumatoid arthritis, and autoimmune vasculitis
  • Administered as intravenous infusion by trained healthcare professionals
  • Requires careful monitoring during and after administration
  • Not suitable during pregnancy or breastfeeding

Therapeutic Uses

  • Non-Hodgkin's lymphoma (NHL) — cancer of B-cells
  • Chronic lymphocytic leukemia (CLL) — slow-growing blood cancer
  • Rheumatoid arthritis — moderate to severe immune-mediated joint disease
  • Granulomatosis with polyangiitis and microscopic polyangiitis — blood vessel inflammation affecting lungs and kidneys
  • Pemphigus vulgaris — autoimmune blistering disease of skin and mucous membranes

How it Works

Xmab 500mg works as a monoclonal antibody by binding to CD20 antigen found on the surface of B-lymphocytes (white blood cells). Once attached, the medication triggers the destruction of these cells. In non-Hodgkin's lymphoma and chronic lymphocytic leukemia, this action directly kills cancer cells. In rheumatoid arthritis, Xmab reduces the production of rheumatoid factor, blocks antigen presentation, and decreases inflammatory chemicals (cytokines), thereby reducing joint inflammation and immune system attacks on healthy tissue.

How to Take

Xmab 500mg Injection must be administered exclusively by a trained doctor or nurse as an intravenous infusion. Do not attempt self-administration. Your healthcare provider will determine the exact dose and treatment duration based on your specific condition severity and overall health status.

Instructions

  • Receive pre-medication from your doctor to reduce potential infusion reactions
  • Allow the healthcare professional to administer the injection slowly into a vein
  • Remain under medical observation during the infusion and for a specified period afterward
  • Report any unusual symptoms or reactions to your doctor immediately
  • Attend all scheduled follow-up appointments to monitor treatment effectiveness

Timing

Administered as scheduled by your oncologist or rheumatologist; not related to meals

Missed dose

If you miss a scheduled infusion appointment, contact your doctor immediately to reschedule as soon as possible. Maintain regular treatment intervals for optimal effectiveness.

Overdose

Xmab 500mg overdose is unlikely due to clinical administration by healthcare professionals. If you have concerns about accidental exposure, contact your doctor or poison control center immediately.

Side Effects

  • Infusion reactions including fever, chills, headache, chest pain, breathing difficulties, throat swelling, and skin rashes (occurring during or within 24 hours of administration)
  • Infection (including blood infections) due to weakened immune response and reduced white blood cell counts
  • Reduced red blood cells (anemia), muscle spasms, diarrhea, nausea, and itchy skin
  • Swelling in the face and body, dizziness, urinary tract infections, and increased sweating
  • Low or high blood pressure changes

Safety Advice

Pregnancy

Unsafe

Xmab 500mg Injection may harm the developing fetus and is not recommended during pregnancy. The medication can cross the placental barrier and potentially affect fetal development.

Tip: Inform your doctor immediately if you are pregnant, suspect pregnancy, or plan to become pregnant. Use effective contraceptive methods during treatment and for 12 months after your last dose.

Breastfeeding

Unsafe

Xmab 500mg passes into breast milk in small amounts and may harm your nursing infant. The safety of this medication in breastfed babies is not established.

Tip: Do not breastfeed while taking Xmab 500mg Injection. Discuss safer infant feeding options with your doctor.

Liver

Consult Doctor

The safety of Xmab in patients with liver disease is not fully established. Importantly, hepatitis B infection may reactivate in some patients, causing severe liver complications. Those with a history of hepatitis B require special monitoring.

Tip: Inform your doctor if you have or previously had liver disease or hepatitis B infection before starting treatment. Your doctor may order liver function tests and monitor you closely.

Lungs

Consult Doctor

The use of Xmab in patients with existing lung disorders is not well-established. Patients with respiratory conditions may require additional monitoring during treatment.

Tip: Inform your doctor if you have any lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), or other respiratory conditions before beginning Xmab therapy.

Alcohol

Unsafe

Consuming alcohol may reduce the effectiveness of Xmab 500mg Injection and potentially increase side effects. Alcohol can impair immune function and interact with the medication's mechanism of action.

Tip: Avoid alcohol consumption entirely while taking Xmab 500mg Injection. Discuss any alcohol use concerns with your healthcare provider.

Driving

Unsafe

Xmab 500mg may cause dizziness, drowsiness, fatigue, and balance problems, all of which impair your ability to drive safely or operate machinery.

Tip: Avoid driving and operating heavy machinery during treatment. Ask someone to drive you to and from medical appointments. Wait until you feel alert before resuming any activities requiring coordination.

Kidney

Consult Doctor

While specific kidney impairment data is limited, patients with kidney disease may require dose adjustments or additional monitoring during Xmab therapy.

Tip: Inform your doctor if you have kidney disease or reduced kidney function. Your doctor may monitor kidney function throughout treatment.

FAQs

What are the special precautions I should be aware of before starting treatment with Xmab 500mg injection?
Before beginning Xmab 500mg treatment, inform your doctor of any allergies to rituximab or other ingredients, weakened immune system, active infections, heart disease, heart failure, or breathing problems. Additionally, disclose any history of hepatitis B infection, as the virus may reactivate during treatment. Women of childbearing age should use effective contraception during treatment and for 12 months after the last dose. Avoid alcohol consumption, as it may reduce medication effectiveness. If you have lung or liver disorders, discuss these conditions with your doctor, as they may require special monitoring during your treatment course.
What are Xmab 500mg infusion-related reactions?
Infusion-related reactions are unwanted symptoms that may occur during the intravenous infusion of Xmab or within 24 hours after administration. These reactions can include increased blood pressure, chest pain, headache, difficulty breathing, vomiting, skin rashes, and throat swelling. Other symptoms may include fever and chills. Most infusion reactions are mild to moderate, but some can be serious. Your doctor will administer pre-medication to help prevent these reactions and will monitor you closely during and after the infusion. Inform your healthcare professional immediately if you experience any of these symptoms so appropriate measures can be taken.
What will be the most important thing to monitor during Xmab 500mg injection?
The most critical aspect to monitor during Xmab 500mg treatment is the development of infusion-related reactions, as these can occur during administration or within 24 hours afterward. Your healthcare team will closely observe you during the infusion for signs of fever, chills, breathing difficulties, chest pain, or skin reactions. Additionally, your doctor will monitor your blood counts regularly, particularly red blood cells and white blood cells, since Xmab affects these cell populations. If you have hepatitis B history, liver function tests and hepatitis B monitoring will be essential. Any signs of new or worsening infections should be reported immediately to your healthcare provider.
Is weight gain a side effect of Xmab 500mg injection?
Weight gain is not listed as a common or well-documented side effect of Xmab 500mg Injection in clinical studies. The most frequently reported side effects relate to infusion reactions, infections, blood cell reductions, and gastrointestinal symptoms such as diarrhea and nausea. However, individual responses to medications vary, and some patients may experience changes in appetite or fluid retention unrelated to the medication itself. If you notice significant weight changes during treatment, discuss this with your doctor to determine if it is related to your medication, underlying condition, or other factors.
Does Xmab 500mg injection suppress the immune system?
Yes, Xmab 500mg Injection does suppress immune system function by specifically targeting and destroying B-lymphocytes (a type of white blood cell). While this effect is therapeutic for treating blood cancers and autoimmune diseases like rheumatoid arthritis, it does increase your susceptibility to infections. Your immune system becomes weakened during treatment, making you more vulnerable to bacterial, viral, and fungal infections. This is why your doctor will monitor you closely for signs of infection and may prescribe preventive measures. Avoid contact with people who have active infections, practice good hygiene, and report any fever or signs of infection to your healthcare provider immediately. Your immune system function typically begins to recover after treatment completion, though full restoration may take several months.

Drug Interactions

Several medications may interact with Xmab 500mg Injection, potentially reducing its effectiveness or causing additional side effects. It is essential to inform your healthcare provider about all medications you currently take, including prescription drugs, over-the-counter medicines, vitamins, supplements, and herbal products.

Major interactions

  • Blood pressure medications and heart condition drugs
  • Other immunosuppressant medications
  • Certain vaccines (may be less effective during treatment)

Precautions

  • Inform your doctor about all current medications before starting Xmab
  • Do not start new medications without consulting your healthcare provider
  • Inform your doctor if you are taking medications for heart conditions
  • Discuss timing of any necessary vaccinations with your medical team

Important

Certain drug combinations may reduce Xmab's effectiveness or increase unwanted side effects. Always consult your healthcare provider before adding or stopping any medication during Xmab treatment.

Storage Details

🌡 Store at 2°C to 8°C (36°F to 46°F) in a refrigerator

Keep in the original container in a designated area away from direct light

  • Do not freeze the injection
  • Keep away from reach of children and pets
  • Do not use if the solution appears cloudy, discolored, or contains particles
  • Store away from extreme heat and moisture

Fact Box

Active Ingredient
Rituximab 500mg
Drug Class
Anti-CD20 Monoclonal Antibody
Therapeutic Use
Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Rheumatoid Arthritis, Vasculitis, Pemphigus Vulgaris
Prescription Required
Yes
Administration Route
Intravenous Infusion
Storage Temperature
2°C to 8°C (Refrigerated)

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Quality Guaranteed

Guaranteed Temperature-Controlled Handling and Shipping — We maintain strict cold chain compliance for temperature-sensitive medicines from storage to delivery.

1

Carefully Packed

Every order is carefully packaged to maintain the required temperature for cold chain medicines and vaccines.

2

Verified Storage

Our pharmaceutical storage facilities are closely monitored and verified to ensure proper temperature conditions.

3

Insulated Shipping

We use insulated containers and temperature monitors for safe transport of temperature-sensitive medicines.

Rx Prescription Required

This medicine requires a valid prescription from a registered medical practitioner (doctor). As per Indian regulations, prescription-only medicines cannot be sold without a valid Rx.

You will need to upload your prescription during checkout. We accept clear images or PDF of your doctor's prescription.

Consult your doctor before taking any medicine. Never self-medicate with prescription drugs.

Medical Disclaimer

MedsRight is committed to providing consumers with reliable, accurate, and expert-validated healthcare information. All content published on this website is intended solely for general informational and educational purposes. It should not be considered a substitute for professional medical advice, diagnosis, or treatment.

We strongly encourage you to consult a qualified doctor or healthcare professional for guidance regarding any medical condition, symptoms, or medications. Never ignore or postpone seeking professional medical advice because of information you have read on MedsRight.

Our goal is to empower patients with trustworthy information while fully respecting and preserving the integrity of the doctor–patient relationship.

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